BDBM50037471 (6R,11S)-3,6,11-Trimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::CHEMBL117128

SMILES C[C@@H]1C2Cc3ccc(O)cc3[C@]1(C)CCN2C

InChI Key InChIKey=YGSVZRIZCHZUHB-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50037471   

TargetSigma non-opioid intracellular receptor 1(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50037471((6R,11S)-3,6,11-Trimethyl-1,2,3,4,5,6-hexahydro-2,...)
Affinity DataKi:  1.33E+3nMAssay Description:Inhibition against sigma receptor using displacement of 3 nM [3H]pentazocine in homogenate of guinea pig brain cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50037471((6R,11S)-3,6,11-Trimethyl-1,2,3,4,5,6-hexahydro-2,...)
Affinity DataKi:  1.38E+3nMAssay Description:Inhibition against mu receptor from displacement studies using 0.5 nM [3H]-DAMGO in rhesus monkey cortex membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50037471((6R,11S)-3,6,11-Trimethyl-1,2,3,4,5,6-hexahydro-2,...)
Affinity DataKi:  3.78E+3nMAssay Description:Inhibition against kappa receptor from displacement studies using 1.5 nM [3H]U-69593 in rhesus monkey cortex membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50037471((6R,11S)-3,6,11-Trimethyl-1,2,3,4,5,6-hexahydro-2,...)
Affinity DataKi:  4.97E+3nMAssay Description:Inhibition against mu receptor using [3H]DAMGO in homogenate of rat brain cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50037471((6R,11S)-3,6,11-Trimethyl-1,2,3,4,5,6-hexahydro-2,...)
Affinity DataKi:  7.00E+3nMAssay Description:Inhibition against delta receptor from displacement studies using 1.5 nM [3H]DPDPE in rhesus monkey cortex membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed