BDBM50038159 (R)-3-Amino-1-hydroxy-pyrrolidin-2-one::CHEMBL335231

SMILES N[C@@H]1CCN(O)C1=O

InChI Key InChIKey=HCKUBNLZMKAEIN-GSVOUGTGSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50038159   

TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038159((R)-3-Amino-1-hydroxy-pyrrolidin-2-one | CHEMBL335...)
Affinity DataKi:  2.50E+3nMAssay Description:Compound was evaluated for in vitro inhibition of cortical neuron at NMDA receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50038159((R)-3-Amino-1-hydroxy-pyrrolidin-2-one | CHEMBL335...)
Affinity DataIC50:  1.25E+4nMAssay Description:Inhibition of [3H]-glycine binding to rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50038159((R)-3-Amino-1-hydroxy-pyrrolidin-2-one | CHEMBL335...)
Affinity DataIC50:  1.25E+4nMAssay Description:Inhibition of [3H]-glycine binding to rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails Article