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BDBM50038353 3-Chloro-5,8,9,13b-tetrahydro-6H-isoquino[1,2-a]isoquinolin-2-ol::CHEMBL323771

SMILES: Oc1cc2C3N(CCc4ccccc34)CCc2cc1Cl

InChI Key: InChIKey=DHNFZLUQSVLKHW-UHFFFAOYSA-N

Data: 2 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50038353   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
DOPAMINE


(RAT)
BDBM50038353
PNG
(3-Chloro-5,8,9,13b-tetrahydro-6H-isoquino[1,2-a]is...)
Show SMILES Oc1cc2C3N(CCc4ccccc34)CCc2cc1Cl
Show InChI InChI=1S/C17H16ClNO/c18-15-9-12-6-8-19-7-5-11-3-1-2-4-13(11)17(19)14(12)10-16(15)20/h1-4,9-10,17,20H,5-8H2
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
830n/an/an/an/an/an/an/an/a



University of North Carolina

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D1 using [3H]-SCH-23,390 was determined in rat striatal membranes


J Med Chem 37: 4317-28 (1995)

Checked by Author
Article DOI: 10.1021/jm00051a008
BindingDB Entry DOI: 10.7270/Q2NC607Q
More data for this
Ligand-Target Pair
DOPAMINE


(RAT)
BDBM50038353
PNG
(3-Chloro-5,8,9,13b-tetrahydro-6H-isoquino[1,2-a]is...)
Show SMILES Oc1cc2C3N(CCc4ccccc34)CCc2cc1Cl
Show InChI InChI=1S/C17H16ClNO/c18-15-9-12-6-8-19-7-5-11-3-1-2-4-13(11)17(19)14(12)10-16(15)20/h1-4,9-10,17,20H,5-8H2
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>5.00E+3n/an/an/an/an/an/an/an/a



University of North Carolina

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine (D1) receptor using [3H]-spiperone was determined in rat striatal membranes


J Med Chem 37: 4317-28 (1995)

Checked by Author
Article DOI: 10.1021/jm00051a008
BindingDB Entry DOI: 10.7270/Q2NC607Q
More data for this
Ligand-Target Pair