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BDBM50038914 1-[4-(2-Chloro-phenyl)-6,8-dimethyl-quinolin-3-yl]-3-(2,6-diisopropyl-phenyl)-urea::CHEMBL65602

SMILES: CC(C)c1cccc(C(C)C)c1NC(=O)Nc1cnc2c(C)cc(C)cc2c1-c1ccccc1Cl

InChI Key: InChIKey=LRZCGUKHIAQMQY-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50038914   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sterol O-acyltransferase, Soat


(Rattus norvegicus)
BDBM50038914
PNG
(1-[4-(2-Chloro-phenyl)-6,8-dimethyl-quinolin-3-yl]...)
Show SMILES CC(C)c1cccc(C(C)C)c1NC(=O)Nc1cnc2c(C)cc(C)cc2c1-c1ccccc1Cl
Show InChI InChI=1S/C30H32ClN3O/c1-17(2)21-11-9-12-22(18(3)4)29(21)34-30(35)33-26-16-32-28-20(6)14-19(5)15-24(28)27(26)23-10-7-8-13-25(23)31/h7-18H,1-6H3,(H2,33,34,35)
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 28n/an/an/an/an/an/a



Takeda Chemical Industries, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomes


J Med Chem 37: 2079-84 (1994)


Article DOI: 10.1021/jm00039a020
BindingDB Entry DOI: 10.7270/Q23F4NPC
More data for this
Ligand-Target Pair