BDBM50039154 10,13-Dimethyl-1,2,7,8,9,10,11,12,13,14,15,16-dodecahydro-cyclopenta[a]phenanthren-17-one::CHEMBL71152

SMILES CC12CCC3C(CC=C4C=CCCC34C)C1CCC2=O

InChI Key InChIKey=NINLAYUXSUKKHW-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50039154   

TargetAromatase(Human)
Tohoku College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50039154(10,13-Dimethyl-1,2,7,8,9,10,11,12,13,14,15,16-dode...)
Affinity DataKi:  58nMAssay Description:The binding affinity was determined on Cytochrome P450 19A1 by analysis of Dixon plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50039154(10,13-Dimethyl-1,2,7,8,9,10,11,12,13,14,15,16-dode...)
Affinity DataIC50: 340nMAssay Description:In vitro competitive inhibitory activity was measured on Cytochrome P450 19A1 of human placental microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed