BDBM50039234 1-{2-[Tris-(4-methoxy-phenyl)-methoxy]-ethyl}-piperidine-3-carboxylic acid::CHEMBL432737
SMILES COc1ccc(cc1)C(OCCN1CCCC(C1)C(O)=O)(c1ccc(OC)cc1)c1ccc(OC)cc1
InChI Key InChIKey=VDLDUZLDZBVOAS-UHFFFAOYSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50039234
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Synaptic Pharmaceutical
Curated by ChEMBL
Synaptic Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 2.33E+5nMAssay Description:Inhibitory activity against human GABA transporter-1 (hGAT1)More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 2(Rattus norvegicus)
Synaptic Pharmaceutical
Curated by ChEMBL
Synaptic Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibitory activity against rat GABA transporter-2 (rGAT2)More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 3(Homo sapiens (Human))
Synaptic Pharmaceutical
Curated by ChEMBL
Synaptic Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against human sodium and chloride dependent GABA transporter 3More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent betaine transporter(Homo sapiens (Human))
Isf College Of Pharmacy
Curated by ChEMBL
Isf College Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 1.40E+5nMAssay Description:Inhibition of human BGT-1 expressed in mouse L-M(TK-) cells assessed as inhibition of [3H]GABA uptakeMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 3(Homo sapiens (Human))
Synaptic Pharmaceutical
Curated by ChEMBL
Synaptic Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human GAT-3 expressed in mouse L-M(TK-) cells assessed as inhibition of [3H]GABA uptakeMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 2(Rattus norvegicus)
Synaptic Pharmaceutical
Curated by ChEMBL
Synaptic Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of rat GAT-2 expressed in mouse L-M(TK-) cells assessed as inhibition of [3H]GABA uptakeMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Synaptic Pharmaceutical
Curated by ChEMBL
Synaptic Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of human GAT-1 expressed in mouse L-M(TK-) cells assessed as inhibition of [3H]GABA uptakeMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent betaine transporter(Homo sapiens (Human))
Isf College Of Pharmacy
Curated by ChEMBL
Isf College Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 2.08E+5nMAssay Description:Inhibition of human GABA transporter (hBGT-1) activity.More data for this Ligand-Target Pair