BDBM50039817 1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-4-propyl-piperazine::CHEMBL27590

SMILES CCCN1CCN(CC1)c1cccc2OCCOc12

InChI Key InChIKey=UYKRXLMKBFTSIL-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50039817   

Target5-hydroxytryptamine receptor 1A(Rat)
University of Lausanne

Curated by ChEMBL
LigandPNGBDBM50039817(1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-4-propyl-pip...)
Affinity DataKi:  79nMAssay Description:Binding affinity of a compound to rat brain 5-hydroxytryptamine 1A (serotonin) receptor assayed by radiolabeled [3H]-8-OH-DPAT ligand displacementMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Lausanne

Curated by ChEMBL
LigandPNGBDBM50039817(1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-4-propyl-pip...)
Affinity DataKi:  80nMAssay Description:Binding affinity to displace [3H]2-(di-N-propylamino)-8-hydroxy-tetralin from 5-hydroxytryptamine 1A (5-HT1A) receptor in rat frontal cortex homogena...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Lausanne

Curated by ChEMBL
LigandPNGBDBM50039817(1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-4-propyl-pip...)
Affinity DataKi:  80nMAssay Description:Displacement of radioligand [3H]2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed