BDBM50039993 CHEMBL330186::[(S)-1-(3-Ethylcarbamoyl-propylcarbamoyl)-3-methyl-butyl]-carbamic acid benzyl ester

SMILES CCNC(=O)CCCNC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1

InChI Key InChIKey=YYVPOIBILWMYMW-KRWDZBQOSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50039993   

TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Alkermes

Curated by ChEMBL
LigandPNGBDBM50039993(CHEMBL330186 | [(S)-1-(3-Ethylcarbamoyl-propylcarb...)
Affinity DataKi:  109nMAssay Description:In vitro inhibition of porcine erythrocyte calpain 1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Alkermes

Curated by ChEMBL
LigandPNGBDBM50039993(CHEMBL330186 | [(S)-1-(3-Ethylcarbamoyl-propylcarb...)
Affinity DataKi:  109nMAssay Description:In vitro inhibition of porcine erythrocyte calpain 1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
Alkermes

Curated by ChEMBL
LigandPNGBDBM50039993(CHEMBL330186 | [(S)-1-(3-Ethylcarbamoyl-propylcarb...)
Affinity DataKi:  122nMAssay Description:Tested for inhibitory activity on bovine calpain 2 from heartMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
Alkermes

Curated by ChEMBL
LigandPNGBDBM50039993(CHEMBL330186 | [(S)-1-(3-Ethylcarbamoyl-propylcarb...)
Affinity DataKi:  138nMAssay Description:Tested for inhibitory activity on human calpain II from placentaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Bos taurus)
Alkermes

Curated by ChEMBL
LigandPNGBDBM50039993(CHEMBL330186 | [(S)-1-(3-Ethylcarbamoyl-propylcarb...)
Affinity DataKi:  138nMAssay Description:Tested for inhibitory activity on bovine calpain II from heartMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Alkermes

Curated by ChEMBL
LigandPNGBDBM50039993(CHEMBL330186 | [(S)-1-(3-Ethylcarbamoyl-propylcarb...)
Affinity DataKi:  210nMAssay Description:Tested for inhibitory activity on human calpain 1 from erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed