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BDBM50040166 3-Allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL418705

SMILES: COc1cccc2CC[C@H]3C(CCN3CC=C)c12

InChI Key: InChIKey=VRRJFCMGNMFNOE-KZUDCZAMSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50040166   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50040166
PNG
(3-Allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo...)
Show SMILES COc1cccc2CC[C@H]3C(CCN3CC=C)c12
Show InChI InChI=1S/C16H21NO/c1-3-10-17-11-9-13-14(17)8-7-12-5-4-6-15(18-2)16(12)13/h3-6,13-14H,1,7-11H2,2H3/t13?,14-/m0/s1
UniProtKB/SwissProt
UniProtKB/TrEMBL

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PC cid
PC sid
UniChem

Similars

Article
PubMed
49n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity against [3H]-8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampus


J Med Chem 36: 1053-68 (1993)


Article DOI: 10.1021/jm00060a014
BindingDB Entry DOI: 10.7270/Q29S1Q3R
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50040166
PNG
(3-Allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo...)
Show SMILES COc1cccc2CC[C@H]3C(CCN3CC=C)c12
Show InChI InChI=1S/C16H21NO/c1-3-10-17-11-9-13-14(17)8-7-12-5-4-6-15(18-2)16(12)13/h3-6,13-14H,1,7-11H2,2H3/t13?,14-/m0/s1
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PC sid
UniChem

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Article
PubMed
77n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity against [3H]-U-86,170-labeled dopamine receptor D2 in cloned CHO cells


J Med Chem 36: 1053-68 (1993)


Article DOI: 10.1021/jm00060a014
BindingDB Entry DOI: 10.7270/Q29S1Q3R
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A (5HT1A)


(Mus musculus (Mouse))
BDBM50040166
PNG
(3-Allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo...)
Show SMILES COc1cccc2CC[C@H]3C(CCN3CC=C)c12
Show InChI InChI=1S/C16H21NO/c1-3-10-17-11-9-13-14(17)8-7-12-5-4-6-15(18-2)16(12)13/h3-6,13-14H,1,7-11H2,2H3/t13?,14-/m0/s1
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
100n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Compound was evaluated for the binding affinity against [3H]-8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in cloned CHO cells


J Med Chem 36: 1053-68 (1993)


Article DOI: 10.1021/jm00060a014
BindingDB Entry DOI: 10.7270/Q29S1Q3R
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50040166
PNG
(3-Allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo...)
Show SMILES COc1cccc2CC[C@H]3C(CCN3CC=C)c12
Show InChI InChI=1S/C16H21NO/c1-3-10-17-11-9-13-14(17)8-7-12-5-4-6-15(18-2)16(12)13/h3-6,13-14H,1,7-11H2,2H3/t13?,14-/m0/s1
PDB

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PC sid
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Article
PubMed
270n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Binding affinity against [3H]-raclopride-labeled dopamine receptor D2 in rat striatum.


J Med Chem 36: 1053-68 (1993)


Article DOI: 10.1021/jm00060a014
BindingDB Entry DOI: 10.7270/Q29S1Q3R
More data for this
Ligand-Target Pair