BDBM50040241 3-Fluoro-6-(4-methyl-piperazin-1-yl)-11H-dibenzo[b,e]azepine::3-Fluoro-6-(4-methyl-piperazin-1-yl)-11H-dibenzo[b,e]azepine(fluperlapine)::CHEMBL63756::Fluperlapine

SMILES: CN1CCN(CC1)C1=Nc2cc(F)ccc2Cc2ccccc12

InChI Key: InChIKey=OBWGMKKHCLHVIE-UHFFFAOYSA-N

Data: 30 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 30 hits for monomerid = 50040241   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serotonin 2 (5-HT2) receptor (Rat)	BDBM50040241 (CHEMBL63756 | 3-Fluoro-6-(4-methyl-piperazin-1-yl)...) Show SMILES Show InChI	GoogleScholar	UniChem		3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 7 (Rat)	BDBM50040241 (CHEMBL63756 | 3-Fluoro-6-(4-methyl-piperazin-1-yl)...) Show SMILES Show InChI	GoogleScholar	UniChem		4.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2A (Rat)	BDBM50040241 (CHEMBL63756 | 3-Fluoro-6-(4-methyl-piperazin-1-yl)...) Show SMILES Show InChI	GoogleScholar	UniChem		6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2A (Rat)	BDBM50040241 (CHEMBL63756 | 3-Fluoro-6-(4-methyl-piperazin-1-yl)...) Show SMILES Show InChI	GoogleScholar	UniChem		7.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2A (Rat)	BDBM50040241 (CHEMBL63756 | 3-Fluoro-6-(4-methyl-piperazin-1-yl)...) Show SMILES Show InChI	GoogleScholar	UniChem		7.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M1 (Human)	BDBM50040241 (CHEMBL63756 | 3-Fluoro-6-(4-methyl-piperazin-1-yl)...) Show SMILES Show InChI	GoogleScholar	UniChem		8.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M4 (Human)	BDBM50040241 (CHEMBL63756 | 3-Fluoro-6-(4-methyl-piperazin-1-yl)...) Show SMILES Show InChI	GoogleScholar	UniChem		14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 6 (Rat)	BDBM50040241 (CHEMBL63756 | 3-Fluoro-6-(4-methyl-piperazin-1-yl)...) Show SMILES Show InChI	GoogleScholar	UniChem		16.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M5 (Human)	BDBM50040241 (CHEMBL63756 | 3-Fluoro-6-(4-methyl-piperazin-1-yl)...) Show SMILES Show InChI	GoogleScholar	UniChem		17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2C (Rat)	BDBM50040241 (CHEMBL63756 | 3-Fluoro-6-(4-methyl-piperazin-1-yl)...) Show SMILES Show InChI	GoogleScholar	UniChem		18.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2C (Rat)	BDBM50040241 (CHEMBL63756 | 3-Fluoro-6-(4-methyl-piperazin-1-yl)...) Show SMILES Show InChI	GoogleScholar	UniChem		18.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2C (Rat)	BDBM50040241 (CHEMBL63756 | 3-Fluoro-6-(4-methyl-piperazin-1-yl)...) Show SMILES Show InChI	GoogleScholar	UniChem		19.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(4) dopamine receptor (Human)	BDBM50040241 (CHEMBL63756 | 3-Fluoro-6-(4-methyl-piperazin-1-yl)...) Show SMILES Show InChI	GoogleScholar	UniChem		21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (Rat)	BDBM50040241 (CHEMBL63756 | 3-Fluoro-6-(4-methyl-piperazin-1-yl)...) Show SMILES Show InChI	GoogleScholar	UniChem		25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 6 (Human)	BDBM50040241 (CHEMBL63756 | 3-Fluoro-6-(4-methyl-piperazin-1-yl)...) Show SMILES Show InChI	GoogleScholar	UniChem		29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M3 (Human)	BDBM50040241 (CHEMBL63756 | 3-Fluoro-6-(4-methyl-piperazin-1-yl)...) Show SMILES Show InChI	GoogleScholar	UniChem		41	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2C (Human)	BDBM50040241 (CHEMBL63756 | 3-Fluoro-6-(4-methyl-piperazin-1-yl)...) Show SMILES Show InChI	GoogleScholar	UniChem		56	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M2 (Human)	BDBM50040241 (CHEMBL63756 | 3-Fluoro-6-(4-methyl-piperazin-1-yl)...) Show SMILES Show InChI	GoogleScholar	UniChem		71	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(1A) dopamine receptor (Human)	BDBM50040241 (CHEMBL63756 | 3-Fluoro-6-(4-methyl-piperazin-1-yl)...) Show SMILES Show InChI	GoogleScholar	UniChem		75	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(1A) dopamine receptor (Mouse)	BDBM50040241 (CHEMBL63756 | 3-Fluoro-6-(4-methyl-piperazin-1-yl)...) Show SMILES Show InChI	GoogleScholar	UniChem		85	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(4) dopamine receptor (Rat)	BDBM50040241 (CHEMBL63756 | 3-Fluoro-6-(4-methyl-piperazin-1-yl)...) Show SMILES Show InChI	GoogleScholar	UniChem		130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Rat)	BDBM50040241 (CHEMBL63756 | 3-Fluoro-6-(4-methyl-piperazin-1-yl)...) Show SMILES Show InChI	GoogleScholar	UniChem		132	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Rat)	BDBM50040241 (CHEMBL63756 | 3-Fluoro-6-(4-methyl-piperazin-1-yl)...) Show SMILES Show InChI	GoogleScholar	UniChem		133	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Rat)	BDBM50040241 (CHEMBL63756 | 3-Fluoro-6-(4-methyl-piperazin-1-yl)...) Show SMILES Show InChI	GoogleScholar	UniChem		141	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Rat)	BDBM50040241 (CHEMBL63756 | 3-Fluoro-6-(4-methyl-piperazin-1-yl)...) Show SMILES Show InChI	GoogleScholar	UniChem		141	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Mouse)	BDBM50040241 (CHEMBL63756 | 3-Fluoro-6-(4-methyl-piperazin-1-yl)...) Show SMILES Show InChI	GoogleScholar	UniChem		245	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(3) dopamine receptor (Rat)	BDBM50040241 (CHEMBL63756 | 3-Fluoro-6-(4-methyl-piperazin-1-yl)...) Show SMILES Show InChI	GoogleScholar	UniChem		255	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rat)	BDBM50040241 (CHEMBL63756 | 3-Fluoro-6-(4-methyl-piperazin-1-yl)...) Show SMILES Show InChI	GoogleScholar	UniChem		316	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rat)	BDBM50040241 (CHEMBL63756 | 3-Fluoro-6-(4-methyl-piperazin-1-yl)...) Show SMILES Show InChI	GoogleScholar	UniChem		316	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(1B) dopamine receptor (Rat)	BDBM50040241 (CHEMBL63756 | 3-Fluoro-6-(4-methyl-piperazin-1-yl)...) Show SMILES Show InChI	GoogleScholar	UniChem		510	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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