BDBM50040586 (R)-2-[(S)-3-Methyl-1-((S)-1-methylcarbamoyl-2-phenyl-ethylcarbamoyl)-butylamino]-4-(1-oxo-1,3-dihydro-benzo[f]isoindol-2-yl)-butyric acid::CHEMBL158696

SMILES CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)N[C@H](CCN1Cc2cc3ccccc3cc2C1=O)C(O)=O

InChI Key InChIKey=WKFUXNDEVSIEGA-PKTNWEFCSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50040586   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50040586((R)-2-[(S)-3-Methyl-1-((S)-1-methylcarbamoyl-2-phe...)
Affinity DataIC50:  63nMAssay Description:Activity against human gelatinase (MMP-9).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50040586((R)-2-[(S)-3-Methyl-1-((S)-1-methylcarbamoyl-2-phe...)
Affinity DataIC50:  211nMAssay Description:Activity against human collagenase (MMP-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50040586((R)-2-[(S)-3-Methyl-1-((S)-1-methylcarbamoyl-2-phe...)
Affinity DataIC50:  7.88E+3nMAssay Description:Activity against human stromelysin (MMP-3).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed