BDBM50040727 CHEMBL3353220::US9255110, 7
SMILES COc1cc2ncccc2cc1NC(=O)c1csc2cnc(nc12)N(C)CCN
InChI Key InChIKey=BUJSZRICYLPWCM-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50040727
Affinity DataIC50: 8nMAssay Description:Purified recombinant IRAK-4 protein was incubated with 250 uM synthetic peptide(KKARFSRFAGSSPSQSSMVAR) in 30 ul of kinase buffer including (20 mM MOP...More data for this Ligand-Target Pair
Affinity DataIC50: 983nMAssay Description:Purified recombinant IRAK-4 protein was incubated with 250 uM synthetic peptide(KKARFSRFAGSSPSQSSMVAR) in 30 ul of kinase buffer including (20 mM MOP...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 410nMAssay Description:Inhibition of SYK (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 983nMAssay Description:Inhibition of IRAK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 410nMpH: 7.2 T: 2°CAssay Description:SYK activity is measured by phosphorylation of a peptide substrate (Biotin-EPEGDYEEVLE) with [gamma-33P] ATP. The enzyme reaction was conducted at 20...More data for this Ligand-Target Pair