BDBM50041115 6-p-Tolyl-5H-[1,3]dioxolo[4,5-g]quinolin-8-one::CHEMBL418352

SMILES: Cc1ccc(cc1)-c1cc(O)c2cc3OCOc3cc2n1

InChI Key: InChIKey=OBBCMZTVWBVNPS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50041115   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tubulin (Bos taurus)	BDBM50041115 (6-p-Tolyl-5H-[1,3]dioxolo[4,5-g]quinolin-8-one | C...) Show SMILES Cc1ccc(cc1)-c1cc(O)c2cc3OCOc3cc2n1 Show InChI InChI=1S/C17H13NO3/c1-10-2-4-11(5-3-10)13-7-15(19)12-6-16-17(21-9-20-16)8-14(12)18-13/h2-8H,9H2,1H3,(H,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
School of Pharmacy Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization				J Med Chem 37: 1126-35 (1994) Article DOI: 10.1021/jm00034a010 BindingDB Entry DOI: 10.7270/Q2ZC81XN
					More data for this Ligand-Target Pair