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BDBM50041115 6-p-Tolyl-5H-[1,3]dioxolo[4,5-g]quinolin-8-one::CHEMBL418352

SMILES: Cc1ccc(cc1)-c1cc(O)c2cc3OCOc3cc2n1

InChI Key: InChIKey=OBBCMZTVWBVNPS-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50041115   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tubulin


(Bos taurus)
BDBM50041115
PNG
(6-p-Tolyl-5H-[1,3]dioxolo[4,5-g]quinolin-8-one | C...)
Show SMILES Cc1ccc(cc1)-c1cc(O)c2cc3OCOc3cc2n1
Show InChI InChI=1S/C17H13NO3/c1-10-2-4-11(5-3-10)13-7-15(19)12-6-16-17(21-9-20-16)8-14(12)18-13/h2-8H,9H2,1H3,(H,18,19)
PDB
MMDB

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Similars

Article
PubMed
n/an/a 1.00E+3n/an/an/an/an/an/a



School of Pharmacy

Curated by ChEMBL


Assay Description
Inhibition of tubulin polymerization


J Med Chem 37: 1126-35 (1994)


Article DOI: 10.1021/jm00034a010
BindingDB Entry DOI: 10.7270/Q2ZC81XN
More data for this
Ligand-Target Pair