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BDBM50041130 6-Methoxy-2-phenyl-1H-quinolin-4-one::CHEMBL14120::GNF-PF-117

SMILES: COc1ccc2nc(cc(O)c2c1)-c1ccccc1

InChI Key: InChIKey=CKFBIYVXNYYXAI-UHFFFAOYSA-N

Data: 2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50041130   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tubulin


(Bos taurus)
BDBM50041130
PNG
(6-Methoxy-2-phenyl-1H-quinolin-4-one | CHEMBL14120...)
Show SMILES COc1ccc2nc(cc(O)c2c1)-c1ccccc1
Show InChI InChI=1S/C16H13NO2/c1-19-12-7-8-14-13(9-12)16(18)10-15(17-14)11-5-3-2-4-6-11/h2-10H,1H3,(H,17,18)
PDB
MMDB

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Article
PubMed
n/an/a 2.70E+3n/an/an/an/an/an/a



Institute of Pharmaceutical Chemistry

Curated by ChEMBL


Assay Description
Inhibition of tubulin polymerization


J Med Chem 36: 1146-56 (1993)


Article DOI: 10.1021/jm00061a005
BindingDB Entry DOI: 10.7270/Q2BV7H8S
More data for this
Ligand-Target Pair
Tubulin


(Bos taurus)
BDBM50041130
PNG
(6-Methoxy-2-phenyl-1H-quinolin-4-one | CHEMBL14120...)
Show SMILES COc1ccc2nc(cc(O)c2c1)-c1ccccc1
Show InChI InChI=1S/C16H13NO2/c1-19-12-7-8-14-13(9-12)16(18)10-15(17-14)11-5-3-2-4-6-11/h2-10H,1H3,(H,17,18)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 610n/an/an/an/an/an/a



School of Pharmacy

Curated by ChEMBL


Assay Description
Inhibition of tubulin polymerization


J Med Chem 37: 1126-35 (1994)


Article DOI: 10.1021/jm00034a010
BindingDB Entry DOI: 10.7270/Q2ZC81XN
More data for this
Ligand-Target Pair