BDBM50041281 (3S,8R)-3-Phenyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester::CHEMBL279657

SMILES COC(=O)C1C2CCC(C[C@@H]1c1ccccc1)N2

InChI Key InChIKey=JEZUFWYDKGYUCS-DBBXXEFVSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50041281   

TargetTransporter(Rattus norvegicus)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50041281((3S,8R)-3-Phenyl-8-aza-bicyclo[3.2.1]octane-2-carb...)
Affinity DataIC50:  85nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50041281((3S,8R)-3-Phenyl-8-aza-bicyclo[3.2.1]octane-2-carb...)
Affinity DataIC50:  31nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine (DA) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50041281((3S,8R)-3-Phenyl-8-aza-bicyclo[3.2.1]octane-2-carb...)
Affinity DataIC50:  156nMAssay Description:Inhibition of [3H]paroxetine binding to 5-hydroxytryptamine (5-HT) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed