BDBM50041537 CHEMBL3358402

SMILES CN(C)c1cc2ccn(-c3cccc(-c4cc(Nc5ccc(cn5)N5CCN(C)CC5)c(=O)n(C)c4)c3CO)c(=O)c2cn1

InChI Key InChIKey=MTMDQIGYIOXORW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50041537   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50041537(CHEMBL3358402)
Affinity DataIC50:  431nMAssay Description:Inhibition of BTK (unknown origin) using biotin-labeled peptide substrate incubated for 1 hr by TR-FRET based HTRF kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50041537(CHEMBL3358402)
Affinity DataIC50:  1.03E+3nMAssay Description:Inhibition of BTK in human Ramos cells assessed as reduction in IgM-induced calcium influx incubated for 20 mins by Fluo-4 dye based fluorescence ass...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed