BDBM50041604 3-(4-Chloro-phenyl)-8-((E)-3-iodo-allyl)-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester::CHEMBL39576

SMILES COC(=O)C1C2CCC(CC1c1ccc(Cl)cc1)N2C\C=C\I

InChI Key InChIKey=NHXMCNVSIJECMD-XNWCZRBMSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50041604   

TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of Tennessee At Knoxville

Curated by ChEMBL
LigandPNGBDBM50041604(3-(4-Chloro-phenyl)-8-((E)-3-iodo-allyl)-8-aza-bic...)
Affinity DataKi:  0.690nMAssay Description:Inhibitory constant towards reuptake of [125I]-12 from dopamine transporter in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of Tennessee At Knoxville

Curated by ChEMBL
LigandPNGBDBM50041604(3-(4-Chloro-phenyl)-8-((E)-3-iodo-allyl)-8-aza-bic...)
Affinity DataKi:  3.20nMAssay Description:Inhibitory constant towards reuptake of [125I]-13 from dopamine transporter in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of Tennessee At Knoxville

Curated by ChEMBL
LigandPNGBDBM50041604(3-(4-Chloro-phenyl)-8-((E)-3-iodo-allyl)-8-aza-bic...)
Affinity DataIC50:  6.10nMAssay Description:Inhibition of [3H]WIN-35428 binding to Dopamine transporter in rat striatal synaptic membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed