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BDBM50041870 3-Cyclopentyloxy-4-methoxy-N-(2,3,5,6-tetrafluoro-pyridin-4-yl)-benzamide::CHEMBL296882

SMILES: COc1ccc(cc1OC1CCCC1)C(=O)Nc1c(F)c(F)nc(F)c1F

InChI Key: InChIKey=XKFPKAOBFHPIQI-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50041870   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphodiesterase 4A


(Sus scrofa)
BDBM50041870
PNG
(3-Cyclopentyloxy-4-methoxy-N-(2,3,5,6-tetrafluoro-...)
Show SMILES COc1ccc(cc1OC1CCCC1)C(=O)Nc1c(F)c(F)nc(F)c1F
Show InChI InChI=1S/C18H16F4N2O3/c1-26-11-7-6-9(8-12(11)27-10-4-2-3-5-10)18(25)23-15-13(19)16(21)24-17(22)14(15)20/h6-8,10H,2-5H2,1H3,(H,23,24,25)
UniProtKB/TrEMBL

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 550n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Inhibitory potency against pig aortic PDE IV


J Med Chem 37: 1696-703 (1994)


Article DOI: 10.1021/jm00037a021
BindingDB Entry DOI: 10.7270/Q2CF9P5F
More data for this
Ligand-Target Pair