BDBM50041927 5,6,7,8,9,10,11,12,13,14-Decahydro-15-thia-1,3-diaza-cyclododeca[a]indene-2,4-diamine::CHEMBL104770

SMILES Nc1nc(N)c2c3CCCCCCCCCCc3sc2n1

InChI Key InChIKey=JAGIFIWFCDRBDB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50041927   

TargetDihydrofolate reductase(Lactobacillus casei)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50041927(5,6,7,8,9,10,11,12,13,14-Decahydro-15-thia-1,3-dia...)
Affinity DataIC50: 200nMAssay Description:Tested for inhibitory activity against dihydrofolate reductase in Beef liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50041927(5,6,7,8,9,10,11,12,13,14-Decahydro-15-thia-1,3-dia...)
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of rat liver dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Lactobacillus casei)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50041927(5,6,7,8,9,10,11,12,13,14-Decahydro-15-thia-1,3-dia...)
Affinity DataIC50: 1.20E+4nMAssay Description:Tested for inhibitory activity against dihydrofolate reductase in Lactobacillus caseiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli (strain K12))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50041927(5,6,7,8,9,10,11,12,13,14-Decahydro-15-thia-1,3-dia...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of dihydrofolate reductase in pneumocystis carinii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed