BDBM50041928 7-Benzyl-5,6,7,8-tetrahydro-9-thia-1,3,7-triaza-fluorene-2,4-diamine::CHEMBL317017

SMILES Nc1nc(N)c2c3CCN(Cc4ccccc4)Cc3sc2n1

InChI Key InChIKey=IGEXZUWFYCYQFB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50041928   

TargetDihydrofolate reductase(Rat)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50041928(7-Benzyl-5,6,7,8-tetrahydro-9-thia-1,3,7-triaza-fl...)
Affinity DataIC50: 570nMAssay Description:Inhibition of rat liver dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50041928(7-Benzyl-5,6,7,8-tetrahydro-9-thia-1,3,7-triaza-fl...)
Affinity DataIC50: 850nMAssay Description:Tested for inhibitory activity against dihydrofolate reductase in Toxoplasma gondiiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50041928(7-Benzyl-5,6,7,8-tetrahydro-9-thia-1,3,7-triaza-fl...)
Affinity DataIC50: 5.20E+3nMAssay Description:Tested for inhibitory activity against dihydrofolate reductase in pneumocystis cariniiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed