BDBM50041931 5-[2-(2,5-Dimethoxy-phenyl)-ethyl]-thieno[2,3-d]pyrimidine-2,4-diamine::5-[2-(2,5-dimethoxyphenyl)ethyl]thieno[2,3-d]pyrimidine-2,4-diamine::CHEMBL107023

SMILES COc1ccc(c(c1)CCc2csc3c2c(nc(n3)N)N)OC

InChI Key InChIKey=XJFDLPAAAIBWID-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50041931   

TargetDihydrofolate reductase(Rat)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50041931(5-[2-(2,5-Dimethoxy-phenyl)-ethyl]-thieno[2,3-d]py...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of rat liver dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli (strain K12))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50041931(5-[2-(2,5-Dimethoxy-phenyl)-ethyl]-thieno[2,3-d]py...)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of dihydrofolate reductase in Toxoplasma gondii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli (strain K12))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50041931(5-[2-(2,5-Dimethoxy-phenyl)-ethyl]-thieno[2,3-d]py...)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of dihydrofolate reductase in pneumocystis carinii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed