BDBM50041935 5,6,7,8,9,10-Hexahydro-11-thia-1,3-diaza-cycloocta[a]indene-2,4-diamine::CHEMBL108006

SMILES Nc1nc(N)c2c3CCCCCCc3sc2n1

InChI Key InChIKey=NZUZCIKDNIBNIL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50041935   

TargetDihydrofolate reductase(Lactobacillus casei)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50041935(5,6,7,8,9,10-Hexahydro-11-thia-1,3-diaza-cycloocta...)
Affinity DataIC50: 400nMAssay Description:Tested for inhibitory activity against dihydrofolate reductase in Beef liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50041935(5,6,7,8,9,10-Hexahydro-11-thia-1,3-diaza-cycloocta...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of rat liver dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli (strain K12))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50041935(5,6,7,8,9,10-Hexahydro-11-thia-1,3-diaza-cycloocta...)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of dihydrofolate reductase in pneumocystis carinii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Lactobacillus casei)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50041935(5,6,7,8,9,10-Hexahydro-11-thia-1,3-diaza-cycloocta...)
Affinity DataIC50: 4.50E+4nMAssay Description:Tested for inhibitory activity against dihydrofolate reductase in Lactobacillus caseiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed