BDBM50041941 6,7,8,9-Tetrahydro-5H-10-thia-1,3-diaza-benzo[a]azulene-2,4-diamine::CHEMBL325333

SMILES Nc1nc(N)c2c3CCCCCc3sc2n1

InChI Key InChIKey=NQRAEWPXWWCRFD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50041941   

TargetDihydrofolate reductase(Escherichia coli (strain K12))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50041941(6,7,8,9-Tetrahydro-5H-10-thia-1,3-diaza-benzo[a]az...)
Affinity DataIC50: 860nMAssay Description:Inhibition of dihydrofolate reductase in Toxoplasma gondii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50041941(6,7,8,9-Tetrahydro-5H-10-thia-1,3-diaza-benzo[a]az...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of rat liver dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli (strain K12))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50041941(6,7,8,9-Tetrahydro-5H-10-thia-1,3-diaza-benzo[a]az...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of dihydrofolate reductase in pneumocystis carinii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed