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BDBM50042001 CHEMBL3359575

SMILES: Cl.CN1CCCN(CC1)c1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1

InChI Key: InChIKey=HOMKBBBNHWVZLP-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50042001   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))
BDBM50042001
PNG
(CHEMBL3359575)
Show SMILES Cl.CN1CCCN(CC1)c1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1
Show InChI InChI=1S/C25H25Cl2N5O2.ClH/c1-31-11-2-12-32(14-13-31)20-7-3-17(4-8-20)24(33)29-22-9-5-18(26)15-21(22)25(34)30-23-10-6-19(27)16-28-23;/h3-10,15-16H,2,11-14H2,1H3,(H,29,33)(H,28,30,34);1H
PDB
MMDB

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Similars

Article
PubMed
n/an/a 3.60n/an/an/an/an/an/a



Astellas Pharma Inc

Curated by ChEMBL


Assay Description
Inhibition of human factor 10a using S-2222 chromogenic substrate assessed as hydrolysis by microplate reader


Bioorg Med Chem 23: 277-89 (2015)


Article DOI: 10.1016/j.bmc.2014.11.042
BindingDB Entry DOI: 10.7270/Q2P55Q4X
More data for this
Ligand-Target Pair