BDBM50042263 4'-(4-Oxo-2-phenyl-1,3-diaza-spiro[4.4]non-1-en-3-ylmethyl)-biphenyl-2-carboxylic acid::CHEMBL423325
SMILES OC(=O)c1ccccc1-c1ccc(CN2C(=O)C3(CCCC3)N=C2c2ccccc2)cc1
InChI Key InChIKey=KTJAGRBGSIVDJU-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50042263
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
Fraunhofer Institute For Translational Medicine And Phamacology Itmp
Curated by ChEMBL
Fraunhofer Institute For Translational Medicine And Phamacology Itmp
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at human AT1 overexpressed in CHO-K1 cells in presence of 10 nM [Val5-angiotensin II measured after 90 mins by HTRF based IP-one ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.20E+3nMAssay Description:Binding affinity for Angiotensin II receptor, type 1 measured by ability to displace [125I]- A II from its specific binding site in rat liver membran...More data for this Ligand-Target Pair