BDBM50042427 CHEMBL118025::[1-(1-Benzylaminooxalyl-propylcarbamoyl)-3-methyl-butyl]-carbamic acid benzyl ester

SMILES CCC(NC(=O)C(CC(C)C)NC(=O)OCc1ccccc1)C(=O)C(=O)NCc1ccccc1

InChI Key InChIKey=QFMKANIDVYDNPI-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50042427   

TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50042427(CHEMBL118025 | [1-(1-Benzylaminooxalyl-propylcarba...)
Affinity DataKi:  22nMpH: 8.0Assay Description:Inhibitory activity of alpha-keto esters towards calpain 2 at pH 8.0More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain small subunit 1/1 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50042427(CHEMBL118025 | [1-(1-Benzylaminooxalyl-propylcarba...)
Affinity DataKi:  200nMAssay Description:Inhibitory activity of alpha-keto esters towards calpain 1 at pH 8.0.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50042427(CHEMBL118025 | [1-(1-Benzylaminooxalyl-propylcarba...)
Affinity DataKi:  200nMAssay Description:Inhibition of the cysteine protease human Calpain 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50042427(CHEMBL118025 | [1-(1-Benzylaminooxalyl-propylcarba...)
Affinity DataKi:  350nMAssay Description:Compound was evaluated for the inhibition of Cysteine protease Calpain 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Bos taurus (bovine))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50042427(CHEMBL118025 | [1-(1-Benzylaminooxalyl-propylcarba...)
Affinity DataKi:  1.30E+3nMpH: 5.2Assay Description:Inhibition of alpha-keto esters towards cathepsin B at pH 5.2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50042427(CHEMBL118025 | [1-(1-Benzylaminooxalyl-propylcarba...)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of human cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPapain(Carica papaya)
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50042427(CHEMBL118025 | [1-(1-Benzylaminooxalyl-propylcarba...)
Affinity DataKi:  3.80E+4nMpH: 6.0Assay Description:Inhibitory activity of alpha-ketoesters towards papain at pH 6.0More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed