BDBM50042640 CHEMBL332580::Sodium; 7-[4-(3-chloro-phenyl)-5-(4-fluoro-phenyl)-2-trifluoromethyl-imidazol-1-yl]-3,5-dihydroxy-heptanoate

SMILES O[C@H](CCn1c(nc(c1-c1ccc(F)cc1)-c1cccc(Cl)c1)C(F)(F)F)C[C@@H](O)CC([O-])=O

InChI Key InChIKey=CDOIXCGFLXAART-QZTJIDSGSA-M

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50042640   

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50042640(CHEMBL332580 | Sodium; 7-[4-(3-chloro-phenyl)-5-(4...)
Affinity DataIC50:  17nMAssay Description:Inhibitory activity against washed rat liver microsomal HMG-CoA reductase (HMGR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed