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BDBM50042719 8-(2-Methyl-imidazol-1-ylmethyl)-1,2,9,10-tetrahydro-8H-3-thia-10b-aza-fluoranthen-7-one::CHEMBL331234

SMILES: Cc1nccn1CC1CCc2c(C1=O)c1cccc3SCCn2c13

InChI Key: InChIKey=LGFXCBJGYUAXAM-UHFFFAOYNA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50042719   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50042719
PNG
(8-(2-Methyl-imidazol-1-ylmethyl)-1,2,9,10-tetrahyd...)
Show SMILES Cc1nccn1CC1CCc2c(C1=O)c1cccc3SCCn2c13
Show InChI InChI=1/C19H19N3OS/c1-12-20-7-8-21(12)11-13-5-6-15-17(19(13)23)14-3-2-4-16-18(14)22(15)9-10-24-16/h2-4,7-8,13H,5-6,9-11H2,1H3
PDB

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
0.770n/an/an/an/an/an/an/an/a



Solvay Duphar B.V.

Curated by ChEMBL


Assay Description
Displacement of [3H]- GR-65,630 binding to 5-hydroxytryptamine 3 receptor in rat brain cortical membranes


J Med Chem 36: 3693-9 (1994)


Article DOI: 10.1021/jm00075a026
BindingDB Entry DOI: 10.7270/Q2NS0SZH
More data for this
Ligand-Target Pair