BDBM50042725 CHEMBL340471::N-[1-(4-Fluoro-benzyl)-piperidin-4-yl]-2,3-dimethoxy-benzamide

SMILES COc1cccc(C(=O)NC2CCN(Cc3ccc(F)cc3)CC2)c1OC

InChI Key InChIKey=KSZBKOKLZQIWFH-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50042725   

TargetD(2) dopamine receptor(Rat)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50042725(N-[1-(4-Fluoro-benzyl)-piperidin-4-yl]-2,3-dimetho...)
Affinity DataKi:  0.380nMAssay Description:Inhibition of [125I]- NCQ 298 binding to D2 receptor of rat striatal tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50042725(N-[1-(4-Fluoro-benzyl)-piperidin-4-yl]-2,3-dimetho...)
Affinity DataKi:  5.90nMAssay Description:In vitro binding affinity on D3 receptor is inhibition of binding of [125I]- NCQ 298 to Sf9 cells infected with recombinant baculovirusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50042725(N-[1-(4-Fluoro-benzyl)-piperidin-4-yl]-2,3-dimetho...)
Affinity DataKi:  1.84E+3nMAssay Description:In vitro binding affinity on 5-hydroxytryptamine 2 receptor is inhibition of binding of [125I]- I-LSD to P11 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
LigandPNGBDBM50042725(N-[1-(4-Fluoro-benzyl)-piperidin-4-yl]-2,3-dimetho...)
Affinity DataKi:  3.00E+3nMAssay Description:In vitro binding affinity on alpha-2 receptor is inhibition of binding of [3H]- rauwolscine to rat cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed