BDBM50042760 CHEMBL121946::H-Tyr-D-Ala-(R or S)CalphaMPhe-Asp-Val-Val-Gly-NH2

SMILES CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@](C)(Cc1ccccc1)NC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(N)=O

InChI Key InChIKey=ANGDKQRQFHANRW-UHFFFAOYSA-N

Data  4 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50042760   

TargetDelta-type opioid receptor(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50042760(H-Tyr-D-Ala-(R or S)CalphaMPhe-Asp-Val-Val-Gly-NH2...)
Affinity DataIC50: 10nMAssay Description:Tested for inhibition of amplification of electrically induced twitch in guinea pig ileum (GPI)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50042760(H-Tyr-D-Ala-(R or S)CalphaMPhe-Asp-Val-Val-Gly-NH2...)
Affinity DataIC50: 10nMAssay Description:Tested for inhibition of amplification of electrically induced twitch in guinea pig ileum (GPI)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50042760(H-Tyr-D-Ala-(R or S)CalphaMPhe-Asp-Val-Val-Gly-NH2...)
Affinity DataKi:  69nMAssay Description:Binding affinity was determined on delta [3H]DPDPE site in rat brain synaptosomes by radioreceptor assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50042760(H-Tyr-D-Ala-(R or S)CalphaMPhe-Asp-Val-Val-Gly-NH2...)
Affinity DataKi:  69.1nMAssay Description:Binding affinity was determined on delta [3H]DPDPE site in rat brain synaptosomes by radioreceptor assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Mouse)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50042760(H-Tyr-D-Ala-(R or S)CalphaMPhe-Asp-Val-Val-Gly-NH2...)
Affinity DataIC50: 554nMAssay Description:Tested for inhibition of amplification of electrically induced twitch in mouse vas deferens (MVD)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Mouse)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50042760(H-Tyr-D-Ala-(R or S)CalphaMPhe-Asp-Val-Val-Gly-NH2...)
Affinity DataIC50: 554nMAssay Description:Tested for inhibition of amplification of electrically induced twitch in mouse vas deferens (MVD)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50042760(H-Tyr-D-Ala-(R or S)CalphaMPhe-Asp-Val-Val-Gly-NH2...)
Affinity DataKi:  1.36E+3nMAssay Description:Binding affinity was determined on mu [3H]DAGO site in rat brain synaptosomes by radioreceptor assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50042760(H-Tyr-D-Ala-(R or S)CalphaMPhe-Asp-Val-Val-Gly-NH2...)
Affinity DataKi:  1.36E+3nMAssay Description:Binding affinity was determined on mu [3H]DAGO site in rat brain synaptosomes by radioreceptor assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed