BDBM50042857 CHEMBL3354494

SMILES CC(C)(c1cc(cc(c1)Cl)Cl)C(=O)c2cc(ccc2OC)C(=O)NCc3ccnc(n3)C#N

InChI Key InChIKey=WCQQOAFZCDVMEP-UHFFFAOYSA-N

Data  5 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50042857   

TargetCathepsin S(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50042857(CHEMBL3354494)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant Cathepsin S using fluorogenic peptide substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2016
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50042857(CHEMBL3354494)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of human recombinant Cathepsin L using fluorogenic peptide substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2016
Entry Details Article
PubMed
TargetCathepsin B(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50042857(CHEMBL3354494)
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of human recombinant Cathepsin B using fluorogenic peptide substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2016
Entry Details Article
PubMed
TargetCathepsin K(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50042857(CHEMBL3354494)
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of human recombinant Cathepsin K using fluorogenic peptide substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2016
Entry Details Article
PubMed
TargetDipeptidyl peptidase 1(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50042857(CHEMBL3354494)
Affinity DataIC50: 6.60E+4nMAssay Description:Inhibition of human recombinant Cathepsin C using fluorogenic peptide substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2016
Entry Details Article
PubMed