BDBM50042993 (2E)-3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)prop-2-en-1-one::2',4,4',6'-tetrahydroxychalcone::CHEMBL338066::Chalconaringenin

SMILES Oc1ccc(\C=C\C(=O)c2c(O)cc(O)cc2O)cc1

InChI Key InChIKey=YQHMWTPYORBCMF-ZZXKWVIFSA-N

Data  2 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50042993   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Tokushima Bunri University

Curated by ChEMBL
LigandPNGBDBM50042993((2E)-3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl...)
Affinity DataIC50:  1.00E+5nMAssay Description:In vitro inhibition against 5-lipoxygenase in RBL-1 cells was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Tokushima Bunri University

Curated by ChEMBL
LigandPNGBDBM50042993((2E)-3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of 5-lipoxygenase in rat RBL1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica (Iqm-Csic)

Curated by ChEMBL
LigandPNGBDBM50042993((2E)-3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl...)
Affinity DataEC50:  4.00E+3nMAssay Description:Positive allosteric modulation at human alpha7 nACHR expressed in Xenopus oocyte assessed as potentiation of 200 uM ACh-induced current at holding po...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed