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BDBM50043273 4'-(5-Acetylamino-2-butyl-benzoimidazol-1-ylmethyl)-biphenyl-2-carboxylic acid::CHEMBL131365

SMILES: CCCCc1nc2cc(NC(C)=O)ccc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O

InChI Key: InChIKey=HYVAXSWWMCGPNH-UHFFFAOYSA-N

Data: 1 IC50  1 Kd

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50043273   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
AGTR1


(RAT)
BDBM50043273
PNG
(4'-(5-Acetylamino-2-butyl-benzoimidazol-1-ylmethyl...)
Show SMILES CCCCc1nc2cc(NC(C)=O)ccc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O
Show InChI InChI=1S/C27H27N3O3/c1-3-4-9-26-29-24-16-21(28-18(2)31)14-15-25(24)30(26)17-19-10-12-20(13-11-19)22-7-5-6-8-23(22)27(32)33/h5-8,10-16H,3-4,9,17H2,1-2H3,(H,28,31)(H,32,33)
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PC cid
PC sid
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Similars

Article
PubMed
n/an/an/a 10n/an/an/an/an/a



Punjabi University

Curated by ChEMBL


Assay Description
Antagonist activity at AT1 receptor in rat aorta


Eur J Med Chem 43: 1808-12 (2008)


Article DOI: 10.1016/j.ejmech.2007.11.008
BindingDB Entry DOI: 10.7270/Q2BZ679K
More data for this
Ligand-Target Pair
Angiotensin II AT1B


(RAT)
BDBM50043273
PNG
(4'-(5-Acetylamino-2-butyl-benzoimidazol-1-ylmethyl...)
Show SMILES CCCCc1nc2cc(NC(C)=O)ccc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O
Show InChI InChI=1S/C27H27N3O3/c1-3-4-9-26-29-24-16-21(28-18(2)31)14-15-25(24)30(26)17-19-10-12-20(13-11-19)22-7-5-6-8-23(22)27(32)33/h5-8,10-16H,3-4,9,17H2,1-2H3,(H,28,31)(H,32,33)
PDB

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UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 460n/an/an/an/an/an/a



Dr. Karl Thomae GmbH

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]-angiotensin-II to angiotensin 1 receptor in rat lung membrane preparation


J Med Chem 36: 4040-51 (1994)


Article DOI: 10.1021/jm00077a007
BindingDB Entry DOI: 10.7270/Q2V98746
More data for this
Ligand-Target Pair