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BDBM50043305 (1-Benzo[b]thiophen-2-yl-cyclohexyl)-methyl-amine::CHEMBL335982

SMILES: CNC1(CCCCC1)c1cc2ccccc2s1

InChI Key: InChIKey=PADRKBFCCOWJKU-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50043305   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Monoamine transporters; Norepininephrine & dopamine


(Rattus norvegicus (rat))
BDBM50043305
PNG
((1-Benzo[b]thiophen-2-yl-cyclohexyl)-methyl-amine ...)
Show SMILES CNC1(CCCCC1)c1cc2ccccc2s1
Show InChI InChI=1S/C15H19NS/c1-16-15(9-5-2-6-10-15)14-11-12-7-3-4-8-13(12)17-14/h3-4,7-8,11,16H,2,5-6,9-10H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 57n/an/an/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Tested for inhibition of radioligand [3H]dopamine (DA) uptake in rat synaptosomes


J Med Chem 36: 4075-81 (1994)


Article DOI: 10.1021/jm00077a011
BindingDB Entry DOI: 10.7270/Q2KK9CFJ
More data for this
Ligand-Target Pair
Monoamine transporters; Norepininephrine & dopamine


(Rattus norvegicus (rat))
BDBM50043305
PNG
((1-Benzo[b]thiophen-2-yl-cyclohexyl)-methyl-amine ...)
Show SMILES CNC1(CCCCC1)c1cc2ccccc2s1
Show InChI InChI=1S/C15H19NS/c1-16-15(9-5-2-6-10-15)14-11-12-7-3-4-8-13(12)17-14/h3-4,7-8,11,16H,2,5-6,9-10H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 270n/an/an/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Tested for radioligand [3H]cocaine displacement from dopamine transporter in rat forebrain


J Med Chem 36: 4075-81 (1994)


Article DOI: 10.1021/jm00077a011
BindingDB Entry DOI: 10.7270/Q2KK9CFJ
More data for this
Ligand-Target Pair
Monoamine transporters; Norepininephrine & dopamine


(Rattus norvegicus (rat))
BDBM50043305
PNG
((1-Benzo[b]thiophen-2-yl-cyclohexyl)-methyl-amine ...)
Show SMILES CNC1(CCCCC1)c1cc2ccccc2s1
Show InChI InChI=1S/C15H19NS/c1-16-15(9-5-2-6-10-15)14-11-12-7-3-4-8-13(12)17-14/h3-4,7-8,11,16H,2,5-6,9-10H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 101n/an/an/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Tested for radioligand [3H]BTCP displacement from dopamine transporter in rat forebrain


J Med Chem 36: 4075-81 (1994)


Article DOI: 10.1021/jm00077a011
BindingDB Entry DOI: 10.7270/Q2KK9CFJ
More data for this
Ligand-Target Pair