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BDBM50043512 CHEMBL136919::[2-Oxo-5-phenyl-3-(3-m-tolyl-ureido)-2,3-dihydro-benzo[e][1,4]diazepin-1-yl]-acetic acid

SMILES: Cc1cccc(NC(=O)NC2N=C(c3ccccc3)c3ccccc3N(CC(O)=O)C2=O)c1

InChI Key: InChIKey=WMUAZVBWFKBBJD-UHFFFAOYNA-N

Data: 2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50043512   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cholecystokinin receptor


(RAT)
BDBM50043512
PNG
(CHEMBL136919 | [2-Oxo-5-phenyl-3-(3-m-tolyl-ureido...)
Show SMILES Cc1cccc(NC(=O)NC2N=C(c3ccccc3)c3ccccc3N(CC(O)=O)C2=O)c1
Show InChI InChI=1/C25H22N4O4/c1-16-8-7-11-18(14-16)26-25(33)28-23-24(32)29(15-21(30)31)20-13-6-5-12-19(20)22(27-23)17-9-3-2-4-10-17/h2-14,23H,15H2,1H3,(H,30,31)(H2,26,28,33)
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UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 76n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of binding of [125I]CCK-8 to cholecystokinin type A receptor in rat pancreatic tissue


J Med Chem 36: 4276-92 (1994)


Article DOI: 10.1021/jm00078a018
BindingDB Entry DOI: 10.7270/Q22J6CH9
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))
BDBM50043512
PNG
(CHEMBL136919 | [2-Oxo-5-phenyl-3-(3-m-tolyl-ureido...)
Show SMILES Cc1cccc(NC(=O)NC2N=C(c3ccccc3)c3ccccc3N(CC(O)=O)C2=O)c1
Show InChI InChI=1/C25H22N4O4/c1-16-8-7-11-18(14-16)26-25(33)28-23-24(32)29(15-21(30)31)20-13-6-5-12-19(20)22(27-23)17-9-3-2-4-10-17/h2-14,23H,15H2,1H3,(H,30,31)(H2,26,28,33)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 380n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of binding of [125I]-CCK-8 to the cholecystokinin type B receptor


J Med Chem 36: 4276-92 (1994)


Article DOI: 10.1021/jm00078a018
BindingDB Entry DOI: 10.7270/Q22J6CH9
More data for this
Ligand-Target Pair