BDBM50043652 CHEMBL3355537

SMILES CN1Cc2cc(Nc3ncc4c(n3)n3ccnc3n(-c3c(F)cccc3Cl)c4=O)ccc2C2(CC2)C1

InChI Key InChIKey=YFRNHMAIZOCUPR-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50043652   

TargetWee1-like protein kinase(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50043652(CHEMBL3355537)
Affinity DataKi: <1nMAssay Description:Inhibition of GST-tagged human Wee1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetWee1-like protein kinase(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50043652(CHEMBL3355537)
Affinity DataEC50:  29nMAssay Description:Inhibition of human Weel1 in human NCI-H1299 cells assessed as phosphorylation of Cdk1 after overnight incubation by ELISA PD assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed