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BDBM50043941 CHEMBL3356014

SMILES: Nc1n[nH]c2cc(ccc12)-c1ccc(NS(=O)(=O)C2CC2)cc1

InChI Key: InChIKey=SIOZRRKLXCSWOF-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50043941   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine/threonine-protein kinase Sgk1


(Homo sapiens (Human))
BDBM50043941
PNG
(CHEMBL3356014)
Show SMILES Nc1n[nH]c2cc(ccc12)-c1ccc(NS(=O)(=O)C2CC2)cc1
Show InChI InChI=1S/C16H16N4O2S/c17-16-14-8-3-11(9-15(14)18-19-16)10-1-4-12(5-2-10)20-23(21,22)13-6-7-13/h1-5,8-9,13,20H,6-7H2,(H3,17,18,19)
PDB
MMDB

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Article
PubMed
n/an/a 1.80E+3n/an/an/an/an/an/a



Sanofi R & D

Curated by ChEMBL


Assay Description
Inhibition of human SGK1 using fluo-5(6)-carboxyfluorescein)-RPRAATF-NH2 fluorescently labeled peptide by substrate phosphorylation assay in presence...


ACS Med Chem Lett 6: 73-8 (2015)


Article DOI: 10.1021/ml5003376
BindingDB Entry DOI: 10.7270/Q28S4RJT
More data for this
Ligand-Target Pair