BDBM50043958 CHEMBL554054::CHEMBL92484::N-(3-Ethyl-phenyl)-N-methyl-N'-naphthalen-1-yl-guanidine

SMILES CCc1cccc(c1)N(C)C(N)=Nc1cccc2ccccc12

InChI Key InChIKey=BFNCJMURTMZBTE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50043958   

TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50043958(CHEMBL554054 | CHEMBL92484 | N-(3-Ethyl-phenyl)-N-...)
Affinity DataIC50:  2.54E+3nMAssay Description:Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensionsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50043958(CHEMBL554054 | CHEMBL92484 | N-(3-Ethyl-phenyl)-N-...)
Affinity DataIC50:  2.54E+3nMAssay Description:Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed