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BDBM50043975 CHEMBL88161::N,N'-Dimethyl-N,N'-di-naphthalen-1-yl-guanidine

SMILES: CN(C(=N)N(C)c1cccc2ccccc12)c1cccc2ccccc12

InChI Key: InChIKey=SEBJCZLKPBAXBL-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50043975   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))
BDBM50043975
PNG
(CHEMBL88161 | N,N'-Dimethyl-N,N'-di-naphthalen-1-y...)
Show SMILES CN(C(=N)N(C)c1cccc2ccccc12)c1cccc2ccccc12
Show InChI InChI=1S/C23H21N3/c1-25(21-15-7-11-17-9-3-5-13-19(17)21)23(24)26(2)22-16-8-12-18-10-4-6-14-20(18)22/h3-16,24H,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 1.07E+4n/an/an/an/an/an/a



Cambridge NeuroScience Inc

Curated by ChEMBL


Assay Description
Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membrane


J Med Chem 37: 260-7 (1994)


Article DOI: 10.1021/jm00028a009
BindingDB Entry DOI: 10.7270/Q2HX1BRZ
More data for this
Ligand-Target Pair