BDBM50044106 CHEMBL3325770

SMILES [H][C@@]12C[C@H](CC)[C@@]3([H])N(C1)CCc1c([nH]c4ccccc14)[C@]3(C2)C(=O)OC

InChI Key

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50044106   

TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
University Of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50044106(CHEMBL3325770)
Affinity DataEC50:  8.00E+3nMAssay Description:Agonist activity at human TRPA1 expressed in T-REx HEK cells assessed as increase in intracellular Ca2+ accumulation by Fluo-4 AM dye based fluoresce...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily M member 8(Mus musculus)
University Of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50044106(CHEMBL3325770)
Affinity DataIC50:  600nMAssay Description:Antagonist activity against mouse TRPM8 expressed in T-REx HEK cells assessed as inhibition of menthol-induced increase in intracellular Ca2+ accumul...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily M member 8(Mus musculus)
University Of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50044106(CHEMBL3325770)
Affinity DataIC50:  600nMAssay Description:Antagonist activity against mouse TRPM8 expressed in T-REx HEK cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ accumula...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
University Of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50044106(CHEMBL3325770)
Affinity DataEC50:  7.00E+3nMAssay Description:Agonist activity at human TRPV1 expressed in T-REx HEK cells assessed as increase in intracellular Ca2+ accumulation by Fluo-4 AM dye based fluoresce...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed