BDBM50044160 CHEMBL3314003
SMILES Fc1ccc(cc1)S(=O)(=O)N1CCCc2ccc(NC(=O)c3c(F)cccc3Cl)cc12
InChI Key InChIKey=YVMQUIHDHWLADX-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50044160
Affinity DataIC50: <1.50E+4nMAssay Description:Inverse agonist activity at human RoRc-LBD expressed in cells assessed as SRC1 to 2 coactivator peptide recruitmentMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+4nMAssay Description:Agonist activity at RoRc-LBD (unknown origin) expressed in HEK293 cells assessed as transcriptional activity by GAL4 reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 11nMAssay Description:Inverse agonist activity at N-terminal 6xHis-tagged human RORc ligand binding domain (241 to 486) expressed in bacterial expression system assessed a...More data for this Ligand-Target Pair
Affinity DataEC50: 29nMAssay Description:Inverse agonist activity at GAL4-fused human RORa expressed in HEK293 cells assessed as suppression of basal transcriptional activity after 20 hrs by...More data for this Ligand-Target Pair
Affinity DataEC50: 820nMAssay Description:Antagonist activity at GAL4-fused human PXR expressed in HEK293 cells assessed as inhibition of T0901317-stimulated transcriptional activity after 20...More data for this Ligand-Target Pair
Affinity DataEC50: 3.90E+3nMAssay Description:Inverse agonist activity at GAL4-fused human RORc expressed in HEK293 cells assessed as suppression of basal transcriptional activity after 20 hrs by...More data for this Ligand-Target Pair
Affinity DataEC50: 3.90E+3nMAssay Description:Antagonist activity at GAL4-fused human LXRalpha expressed in HEK293 cells assessed as inhibition of T0901317-stimulated transcriptional activity aft...More data for this Ligand-Target Pair
Affinity DataEC50: 2.60E+3nMAssay Description:Antagonist activity at GAL4-fused human LXRbeta expressed in HEK293 cells assessed as inhibition of T0901317-stimulated transcriptional activity afte...More data for this Ligand-Target Pair
Affinity DataEC50: 5.30E+3nMAssay Description:Antagonist activity at GAL4-fused human FXR expressed in HEK293 cells assessed as inhibition of T0901317-stimulated transcriptional activity after 20...More data for this Ligand-Target Pair
Affinity DataEC50: 3.40E+3nMAssay Description:Inverse agonist activity at GAL4-fused human RORb expressed in HEK293 cells assessed as suppression of basal transcriptional activity after 20 hrs by...More data for this Ligand-Target Pair