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BDBM50044223 7-{2-[4-(2-Hydroxy-ethyl)-piperazin-1-yl]-ethoxy}-8-methyl-2-morpholin-4-yl-chromen-4-one::CHEMBL60362

SMILES: Cc1c(OCCN2CCN(CCO)CC2)ccc2c1oc(cc2=O)N1CCOCC1

InChI Key: InChIKey=PTMGEVRUWDXITF-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50044223   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Purinergic receptor P2Y12


(Homo sapiens (Human))
BDBM50044223
PNG
(7-{2-[4-(2-Hydroxy-ethyl)-piperazin-1-yl]-ethoxy}-...)
Show SMILES Cc1c(OCCN2CCN(CCO)CC2)ccc2c1oc(cc2=O)N1CCOCC1
Show InChI InChI=1S/C22H31N3O5/c1-17-20(29-15-9-24-6-4-23(5-7-24)8-12-26)3-2-18-19(27)16-21(30-22(17)18)25-10-13-28-14-11-25/h2-3,16,26H,4-15H2,1H3
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PC sid
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Similars

Article
PubMed
n/an/a 1.20E+4n/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against ADP-induced human platelet aggregation


J Med Chem 36: 2026-32 (1993)


Article DOI: 10.1021/jm00066a012
BindingDB Entry DOI: 10.7270/Q2RF5T33
More data for this
Ligand-Target Pair