BDBM50044362 5-Butyl-2-naphthalen-2-ylmethyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::5-Butyl-2-naphthalen-2-ylmethyl-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL86986

SMILES CCCCc1nn(Cc2ccc3ccccc3c2)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1

InChI Key InChIKey=ASSQJXCGYVVNGG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50044362   

TargetType-1 angiotensin II receptor(Rabbit)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50044362(5-Butyl-2-naphthalen-2-ylmethyl-4-[2'-(2H-tetrazol...)
Affinity DataIC50: 27nMAssay Description:In vitro antagonistic activity for angiotensin II receptor, type 1 by displacing 125I[Sar, ILe8 ]AII radioligand in rabbit aorta membrane without usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50044362(5-Butyl-2-naphthalen-2-ylmethyl-4-[2'-(2H-tetrazol...)
Affinity DataIC50: 280nMAssay Description:Displacement of [125I]-angiotensin 2 from angiotensin AT1 receptor in Rattus norvegicus (rat) uterine membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetType-1 angiotensin II receptor B(Rat)
Searle R&D

Curated by ChEMBL
LigandPNGBDBM50044362(5-Butyl-2-naphthalen-2-ylmethyl-4-[2'-(2H-tetrazol...)
Affinity DataIC50: 280nMAssay Description:Inhibition of [125I]angiotensin-II binding to the angiotensin II receptor type 1 in rat uterine membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50044362(5-Butyl-2-naphthalen-2-ylmethyl-4-[2'-(2H-tetrazol...)
Affinity DataIC50: 280nMAssay Description:Displacement of [125I]-angiotensin 2 from angiotensin AT1 receptor in Rattus norvegicus (rat) uterine membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article