BDBM50044436 1-Phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL309711

SMILES c1ccc(cc1)N2CNC(=O)C23CCNCC3

InChI Key InChIKey=HTQWGIHCFPWKAS-UHFFFAOYSA-N

Data  3 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50044436   

Target5-hydroxytryptamine receptor 1A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50044436(1-Phenyl-1,3,8-triaza-spiro[4.5]decan-4-one | CHEM...)
Affinity DataKi: >1.00E+4nMAssay Description:Tested for binding affinity against 5-hydroxytryptamine 1A receptor from rat frontal cortical regions using [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50044436(1-Phenyl-1,3,8-triaza-spiro[4.5]decan-4-one | CHEM...)
Affinity DataKi: >1.00E+4nMAssay Description:Tested for binding affinity against 5-hydroxytryptamine 1C receptor from rat frontal cortical regions using [3H]mesulergine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50044436(1-Phenyl-1,3,8-triaza-spiro[4.5]decan-4-one | CHEM...)
Affinity DataKi: >1.00E+4nMAssay Description:Tested for binding affinity against 5-hydroxytryptamine 2 receptor from rat frontal cortical regions using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed