BDBM50044440 8-(4-Phenoxy-butyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL82436

SMILES O=C1NCN(c2ccccc2)C11CCN(CCCCOc2ccccc2)CC1

InChI Key InChIKey=TZOSRTSWBQKMTN-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50044440   

Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50044440(8-(4-Phenoxy-butyl)-1-phenyl-1,3,8-triaza-spiro[4....)
Affinity DataKi:  30nMAssay Description:Tested for binding affinity against 5-hydroxytryptamine 1A receptor from rat frontal cortical regions using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50044440(8-(4-Phenoxy-butyl)-1-phenyl-1,3,8-triaza-spiro[4....)
Affinity DataKi:  325nMAssay Description:Tested for binding affinity against 5-hydroxytryptamine 2 receptor from rat frontal cortical regions using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50044440(8-(4-Phenoxy-butyl)-1-phenyl-1,3,8-triaza-spiro[4....)
Affinity DataKi: >1.00E+4nMAssay Description:Tested for binding affinity against 5-hydroxytryptamine 1C receptor from rat frontal cortical regions using [3H]-mesulergine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed