BDBM50044456 8-[3-(4-Nitro-phenoxy)-propyl]-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL309992

SMILES [O-][N+](=O)c1ccc(OCCCN2CCC3(CC2)N(CNC3=O)c2ccccc2)cc1

InChI Key InChIKey=ADEWDPHDHCJVIC-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50044456   

TargetSerotonin 2 (5-HT2) receptor(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50044456(8-[3-(4-Nitro-phenoxy)-propyl]-1-phenyl-1,3,8-tria...)
Affinity DataKi:  600nMAssay Description:Tested for binding affinity against 5-hydroxytryptamine 2 receptor from rat frontal cortical regions using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50044456(8-[3-(4-Nitro-phenoxy)-propyl]-1-phenyl-1,3,8-tria...)
Affinity DataKi:  1.16E+3nMAssay Description:Tested for binding affinity against 5-hydroxytryptamine 1A receptor from rat frontal cortical regions using [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50044456(8-[3-(4-Nitro-phenoxy)-propyl]-1-phenyl-1,3,8-tria...)
Affinity DataKi: >1.00E+4nMAssay Description:Tested for binding affinity against 5-hydroxytryptamine 1C receptor from rat frontal cortical regions using [3H]mesulergine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed