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BDBM50044968 8-Fluoro-2-phenyl-1H-quinolin-4-one::CHEMBL15450

SMILES: Oc1cc(nc2c(F)cccc12)-c1ccccc1

InChI Key: InChIKey=XAKOEESVQXECHQ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50044968   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tubulin


(Bos taurus)
BDBM50044968
PNG
(8-Fluoro-2-phenyl-1H-quinolin-4-one | CHEMBL15450)
Show SMILES Oc1cc(nc2c(F)cccc12)-c1ccccc1
Show InChI InChI=1S/C15H10FNO/c16-12-8-4-7-11-14(18)9-13(17-15(11)12)10-5-2-1-3-6-10/h1-9H,(H,17,18)
PDB
MMDB

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Similars

Article
PubMed
n/an/a 1.10E+4n/an/an/an/an/an/a



Institute of Pharmaceutical Chemistry

Curated by ChEMBL


Assay Description
Inhibition of tubulin polymerization


J Med Chem 36: 1146-56 (1993)


Article DOI: 10.1021/jm00061a005
BindingDB Entry DOI: 10.7270/Q2BV7H8S
More data for this
Ligand-Target Pair