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BDBM50045136 1-[1-(4-Hydroxy-benzoyl)-piperidin-4-yl]-3,4-dihydro-1H-quinolin-2-one::CHEMBL60054

SMILES: Oc1ccc(cc1)C(=O)N1CCC(CC1)N1C(=O)CCc2ccccc12

InChI Key: InChIKey=OKSCENUJYGBZLG-UHFFFAOYSA-N

Data: 2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50045136   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Vasopressin V2 Receptor


(Rattus norvegicus (Rat))
BDBM50045136
PNG
(1-[1-(4-Hydroxy-benzoyl)-piperidin-4-yl]-3,4-dihyd...)
Show SMILES Oc1ccc(cc1)C(=O)N1CCC(CC1)N1C(=O)CCc2ccccc12
Show InChI InChI=1S/C21H22N2O3/c24-18-8-5-16(6-9-18)21(26)22-13-11-17(12-14-22)23-19-4-2-1-3-15(19)7-10-20(23)25/h1-6,8-9,17,24H,7,10-14H2
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CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Otsuka Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Ability to displace [3H]- Arginine Vasopressin (AVP) from its specific binding sites in rat liver (V2 receptor)


J Med Chem 36: 2011-7 (1993)


Article DOI: 10.1021/jm00066a010
BindingDB Entry DOI: 10.7270/Q2DZ07BC
More data for this
Ligand-Target Pair
AVPR1A


(RAT)
BDBM50045136
PNG
(1-[1-(4-Hydroxy-benzoyl)-piperidin-4-yl]-3,4-dihyd...)
Show SMILES Oc1ccc(cc1)C(=O)N1CCC(CC1)N1C(=O)CCc2ccccc12
Show InChI InChI=1S/C21H22N2O3/c24-18-8-5-16(6-9-18)21(26)22-13-11-17(12-14-22)23-19-4-2-1-3-15(19)7-10-20(23)25/h1-6,8-9,17,24H,7,10-14H2
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 1.30E+3n/an/an/an/an/an/a



Otsuka Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Ability to displace [3H]- Arginine Vasopressin (AVP) from its specific binding sites in rat liver (V1 receptor)


J Med Chem 36: 2011-7 (1993)


Article DOI: 10.1021/jm00066a010
BindingDB Entry DOI: 10.7270/Q2DZ07BC
More data for this
Ligand-Target Pair