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BDBM50045358 2-Ethyl-4-{[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-amino}-pyrimidine-5-carboxylic acid ethyl ester::CHEMBL89877

SMILES: CCOC(=O)c1cnc(CC)nc1NCc1ccc(cc1)-c1ccccc1-c1nnn[nH]1

InChI Key: InChIKey=QXXZCEYQOMDEBC-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50045358   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
AGTR1


(RAT)
BDBM50045358
PNG
(2-Ethyl-4-{[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmet...)
Show SMILES CCOC(=O)c1cnc(CC)nc1NCc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C23H23N7O2/c1-3-20-24-14-19(23(31)32-4-2)21(26-20)25-13-15-9-11-16(12-10-15)17-7-5-6-8-18(17)22-27-29-30-28-22/h5-12,14H,3-4,13H2,1-2H3,(H,24,25,26)(H,27,28,29,30)
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Similars

PubMed
21n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity against angiotensin II receptor from rat liver


Citation and Details
More data for this
Ligand-Target Pair