BDBM50045615 CHEMBL3314297::US9540323, 206::US9540323, example 206
SMILES CC1(C)CN(c2c1c(ccc2O)-c1cccc(F)c1)c1ccccc1NC(=O)Nc1ccc(OC(F)(F)F)cc1
InChI Key InChIKey=KVIOQXBUMMLWNP-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50045615
Affinity DataKi: 8.5nM ΔG°: -11.0kcal/molepH: 7.4 T: 2°CAssay Description:A SPA membrane binding assay was used to identify inhibitors of [33P] 2MeS-ADP binding to cloned human P2Y1 receptors (The P2Y1 receptor membranes we...More data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Antagonist activity at P2Y1 receptor in platelet-enriched human plasma assessed as 10 uM ADP-induced platelet aggregation preincubated for 1 min foll...More data for this Ligand-Target Pair
Affinity DataIC50: 0.150nMAssay Description:Antagonist activity at P2Y1 receptor in washed human platelets assessed as 1 uM 2-methylthio-ADP-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair